Association between VNTR Polymorphism in Promoter Region of Prodynorphin (PDYN) Gene and Methamphetamine Dependence

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Association between VNTR Polymorphism in Promoter Region of Prodynorphin (PDYN) Gene and Methamphetamine Dependence

AIM Prodynorphin (PDYN; OMIM: 131340) is the precursor of the dynorphin related peptides which plays an important role in drug abuse. Previous studies have been shown that the expression of PDYN is regulated by a genetic polymorphism of VNTR in the promoter region of the gene. MATERIALS AND METHODS The present case-control study was performed on 52 (41 males, 11 females) methamphetamine depen...

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ژورنال

عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences

سال: 2015

ISSN: 1857-9655

DOI: 10.3889/oamjms.2015.079